BDBM50062522 (1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl)cyclopropanecarboxylic acid::(1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl]cyclopropanecarboxylic acid::(1S,2S)-2-[(S)-1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid::(1S,2S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid::(S)-2-[(S)-1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid::2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine::2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid(LY341495)::CHEMBL432038

SMILES N[C@@](CC1c2ccccc2Oc2ccccc12)([C@H]1C[C@@H]1C(O)=O)C(O)=O

InChI Key InChIKey=VLZBRVJVCCNPRJ-KPHUOKFYSA-N

Data  12 KI  25 IC50  5 EC50

PDB links: 13 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50062522   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataKi:  8.20E+3nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataIC50:  1.14E+4nMAssay Description:Concentration required to inhibit metabotropic glutamate receptor 5 activity of rat expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataEC50: >1.00E+5nMAssay Description:Effective concentration for agonistic activity towards metabotropic glutamate receptor 5 of rat expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)
Affinity DataIC50:  8.20E+3nMAssay Description:Antagonistic activity against metabotropic glutamate receptor 5 (mGluR5) was evaluatedMore data for this Ligand-Target Pair